Retinol + PHA Refining Night Cream

Clinically shown to improve skin smoothness by 29%* and tone evenness by 10%*, this overnight treatment combines entrapped retinol for gentle, gradual cell turnover with PHA (gluconolactone) for surface exfoliation and hydration. Infused with sodium hyaluronate, squalane, glycerin, vitamin E, shea butter, and hydrogenated lecithin, it deeply nourishes, supports the skin barrier, and protects against oxidative stress. *Results based on clinical testing. Data on file at Obagi Cosmeceuticals LLC.

Rooted in medical science and driven by innovation, Obagi Medical has redefined what clinical skincare can achieve. With decades of dermatological research behind every formula, they create results-led products that repair, renew, and protect at a cellular level.

• Apply to face in the evening
• Apply sunscreen before sun exposure
• Avoid the eyelids

Entrapped Retinol: A keratolytic agent commonly referred to as Vitamin A. This gold-standard ingredient is known to help unclog pores, reduce excess surface oil, resurface signs of aging, minimize formation of blemishes, and accelerate skin cell turnover for a smoother, brighter complexion, and improved skin texture over time. The innovative slow-release technology uses a microspheres to entrap Retinol, helping to minimize exposure to light and oxygen while ensuring its gradual release into deeper layers of the skin over time, enhancing stability and minimizing the irritation that is typically associated with acids & Vitamin A derivatives. 

Polyhydroxy Acid (PHA - Gluconolactone): A chemical exfoliant that belongs to the hydroxy acids family that exfoliates, smooths skin texture, helps boost hydration, and improves skin tone. 

Sodium Hyaluronate:A humectant that is a derivative of hyaluronic acid (HA) with intense hydration capabilities. 

Vitamin E (Tocopherol): An antioxidant that helps to protect against oxidative damage and helps to nourish skin.

Squalane:A lipid that helps improve hydration and texture while supporting a healthy skin barrier by mimicking skin’s natural sebum to prevent moisture loss.

Glycerin: A powerful humectant that helps support the skin's moisture barrier and hydration.

Hydrogenated Lecithin: An emulsifier that closely mimics the natural lipids found in skin to help maintain hydration. 

Shea Butter: A deeply nourishing emollient that is naturally rich in vitamins A and E, providing intense hydration by sealing in moisture and softening skin.